4-Phenylphenol Explained

4-Phenylphenol, also known as biphenyl-4-ol and 4-hydroxybiphenyl is an organic compound. It is a phenol analog of biphenyl.

Production

4-Phenylphenol can be obtained from the Suzuki coupling of phenylboronic acid with 4-iodophenol in the presence of 10% palladium on carbon and potassium carbonate.[1] [2]

Properties

4-Phenylphenol is a flammable, difficult to ignite, white, scaly solid with a phenol-like odor that is very slightly soluble in water.[3]

Notes and References

  1. Sakurai . Hidehiro . Tsukuda . Tatsuya . Hirao . Toshikazu . Pd/C as a Reusable Catalyst for the Coupling Reaction of Halophenols and Arylboronic Acids in Aqueous Media . The Journal of Organic Chemistry . 1 April 2002 . 67 . 8 . 2721–2722 . 10.1021/jo016342k. 11950328 .
  2. Kuznetsov . A. G. . Korolev . D. N. . Bumagin . N. A. . Pd black in water as an efficient catalyst of the Suzuki reaction . Russian Chemical Bulletin . 2003 . 52 . 8 . 1882–1883 . 10.1023/A:1026097813946. 98139638 .
  3. Web site: GESTIS-Stoffdatenbank . gestis.dguv.de.