4-Phenyl-4-(1-piperidinyl)cyclohexanol explained

4-Phenyl-4-(1-piperidinyl)cyclohexanol, also known as PPC, is an organic chemical which is a metabolite of phencyclidine (PCP).[1] It can be detected in the hair of PCP users.[2]

PPC has been shown to cause increases in locomotor activity in lab mice.[3]

See also

Notes and References

  1. Nabeshima, Toshitaka . Yamaguchi, Kazumasa . Fukaya, Hiroaki . Hiramatsu, Masayuki . Furukawa, Hiroshi . Kameyama, Tsutomu . Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography . Research Communications in Substances of Abuse . 1985 . 6 . 2 . 65–78.
  2. Nakahara, Yuji . Takahashi, Kazunori . Sakamoto, Tomoaki . Tanaka, Akira . Hill, Virginia A. . Baumgartner, Werner A. . Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use . Journal of Analytical Toxicology . 1997 . 21 . 5 . 356–362 . 9288587 . 10.1093/jat/21.5.356. free .
  3. Web site: Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice.

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