4-Isopropylphenol Explained

4-Isopropylphenol is an organic compound with the formula . The molecule consists of an isopropyl group affixed to the para (p-) position of phenol. The compound, a white solid, is produced by the alkylation of phenol with propylene and is relevant to the production of the commodity chemical bisphenol A (BPA). The preparation of isopropylphenols by alkylation of phenol and various cresols with propylene has been well developed. Depending on the catalysts and conditions, products can include, aside from 4-isopropylphenol, 2-isopropylphenol, 2,6-diisopropylphenol, and 2,4,6-2-triisopropylphenol.

The compound undergoes catalytic dehydrogenation to give p-isopropenylphenol.[1]

References

  1. 10.1021/jo01098a012. Preparation of Vinylphenols and Isopropenylphenols . 1958 . Corson . B. B. . Heintzelman . W. J. . Schwartzman . L. H. . Tiefenthal . H. E. . Lokken . R. J. . Nickels . J. E. . Atwood . G. R. . Pavlik . F. J. . The Journal of Organic Chemistry . 23 . 4 . 544–549 .