4-EA-NBOMe explained

4-EA-NBOMe is a substituted amphetamine and 25-NB derivative which has been sold as a designer drug. It was first identified by a forensic laboratory in Germany in 2014,[1] but while its analytical properties and metabolism have been studied,[2] [3] [4] its pharmacology remains unknown.

See also

Notes and References

  1. Web site: EMCDDA–Europol 2014 Annual Report on the implementation of Council Decision 2005/387/JHA . The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) . 2015.
  2. Westphal F, Girreser U, Waldmüller D . Analytical characterization of four new ortho-methoxybenzylated amphetamine-type designer drugs . Drug Testing and Analysis . 8 . 9 . 910–9 . September 2016 . 26606897 . 10.1002/dta.1889 .
  3. Caspar AT, Westphal F, Meyer MR, Maurer HH . LC-high resolution-MS/MS for identification of 69 metabolites of the new psychoactive substance 1-(4-ethylphenyl-)-N-[(2-methoxyphenyl)methyl] propane-2-amine (4-EA-NBOMe) in rat urine and human liver S9 incubates and comparison of its screening power with further MS techniques . Analytical and Bioanalytical Chemistry . 410 . 3 . 897–912 . January 2018 . 28762065 . 10.1007/s00216-017-0526-0 . 206923339 .
  4. Caspar AT, Meyer MR, Maurer HH . Human cytochrome P450 kinetic studies on six N-2-methoxybenzyl (NBOMe)-derived new psychoactive substances using the substrate depletion approach . Toxicology Letters . 285 . 1–8 . March 2018 . 29277574 . 10.1016/j.toxlet.2017.12.017 .

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