| 3-alpha-hydroxycholanate dehydrogenase | |
| Ec Number: | 1.1.1.52 |
| Cas Number: | 9028-57-3 |
| Go Code: | 0047043 |
In enzymology, a 3alpha-hydroxycholanate dehydrogenase is an enzyme that catalyzes the chemical reaction
3alpha-hydroxy-5beta-cholanate + NAD+
\rightleftharpoons
Thus, the two substrates of this enzyme are 3alpha-hydroxy-5beta-cholanate and NAD+, whereas its 3 products are 3-oxo-5beta-cholanate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase. This enzyme is also called alpha-hydroxy-cholanate dehydrogenase.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .