3-oxoacyl-(acyl-carrier-protein) reductase (NADH) explained

3-oxoacyl-[acyl-carrier-protein] reductase (NADH)
Ec Number:	1.1.1.212
Cas Number:	82047-86-7
Go Code:	0047025

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD⁺

\rightleftharpoons 3-oxoacyl-[acyl-carrier-protein] + NADH + H⁺

Thus, the two substrates of this enzyme are (3R)-3-hydroxyacyl-[acyl-carrier-protein] and NAD⁺, whereas its 3 products are 3-oxoacyl-[acyl-carrier-protein], NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD⁺ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).

References

• 10.1111/j.1432-1033.1982.tb06568.x . Caughey I, Kekwick RG . 1982 . The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit . Eur. J. Biochem. . 123 . 553 - 61 . 7075600 . 3 . free .