3-Hydroxyasparagine Explained

3-Hydroxyasparagine also known as β-hydroxyasparagine (beta-hydroxyasparagine) is a modified asparagine amino acid. It appears in posttranslational modification of cbEGF-like domains which can occur in humans and other Eukaryotes. The amino acid code used for this is Hyn. The modified amino acid residue is found in fibrillin-1.[1] This amino acid is also found in urine.[2]

Notes and References

  1. Glanville . RW . Qian . RQ . McClure . DW . Maslen . CL . Calcium binding, hydroxylation, and glycosylation of the precursor epidermal growth factor-like domains of fibrillin-1, the Marfan gene protein. . The Journal of Biological Chemistry . 28 October 1994 . 269 . 43 . 26630–4 . 10.1016/S0021-9258(18)47065-2 . 7929395. free .
  2. Book: Barrett . Graham . Chemistry and Biochemistry of the Amino Acids . 2012 . Springer Science & Business Media . 9789400948327 . 80 . en.

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