3-hydroxyacyl-CoA dehydratase 2 explained

3-hydroxyacyl-CoA dehydratase 2 is a protein that in humans is encoded by the HACD2 gene.^[1]

Function

The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane.

Further reading

• Wang B, Pelletier J, Massaad MJ, Herscovics A, Shore GC . The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B . Mol. Cell. Biol. . 24 . 7 . 2767–78 . 2004 . 15024066 . 371098 . 10.1128/mcb.24.7.2767-2778.2004.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR . Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score . Mol. Med. . 16 . 7–8 . 247–53 . 2010 . 20379614 . 2896464 . 10.2119/molmed.2009.00159 .

Notes and References

1. Web site: Entrez Gene: 3-hydroxyacyl-CoA dehydratase 2. 2017-09-22.