3-dehydroshikimate dehydratase explained

3-dehydroshikimate dehydratase
Ec Number:4.2.1.118

3-dehydroshikimate dehydratase is an enzyme with systematic name 3-dehydroshikimate hydro-lyase.[1] [2] This enzyme catalyses the following chemical reaction

3-dehydro-shikimate

\rightleftharpoons

3,4-dihydroxybenzoate + H2O

This enzyme catalyses an early step in the biosynthesis of petrobactin.

Notes and References

  1. Fox DT, Hotta K, Kim CY, Koppisch AT . The missing link in petrobactin biosynthesis: asbF encodes a (−)-3-dehydroshikimate dehydratase . Biochemistry . 47 . 47 . 12251–3 . November 2008 . 18975921 . 10.1021/bi801876q .
  2. Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH . Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis . Proceedings of the National Academy of Sciences of the United States of America . 105 . 44 . 17133–8 . November 2008 . 18955706 . 2579390 . 10.1073/pnas.0808118105 . 2008PNAS..10517133P . free .