| 3-carboxy-cis,cis-muconate cycloisomerase | |
| Ec Number: | 5.5.1.2 |
| Cas Number: | 9075-77-8 |
| Go Code: | 0047472 |
In enzymology, a 3-carboxy-cis,cis-muconate cycloisomerase is an enzyme that catalyzes the chemical reaction
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate
\rightleftharpoons
Hence, this enzyme has one substrate, 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, cis,cis-butadiene-1,2,4-tricarboxylate.
This enzyme belongs to the family of isomerases, specifically intramolecular lyases. The systematic name of this enzyme class is 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Other names in common use include beta-carboxymuconate lactonizing enzyme, and 3-carboxymuconolactone hydrolase. This enzyme participates in benzoate degradation via hydroxylation.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .