3-Methylamphetamine Explained

3-Methylamphetamine (3-MeA; PAL-314) is a stimulant drug from the amphetamine family. It is self-administered by mice to a similar extent to 4-fluoroamphetamine and has comparable properties as a monoamine releaser,^[1] although with a more balanced release of all three monoamines, as opposed to the more dopamine/noradrenaline selective fluoro analogues.^[2]

See also

• 2-Methylamphetamine
• 3-Methylmethamphetamine
• 4-Methylamphetamine
• 3,4-Dimethylamphetamine
• 3-Trifluoromethylamphetamine

Notes and References

1. Wee S, Anderson KG, Baumann MH, Rothman RB, Blough BE, Woolverton WL . Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs . The Journal of Pharmacology and Experimental Therapeutics . 313 . 2 . 848–54 . May 2005 . 15677348 . 10.1124/jpet.104.080101 . 12135483 .
2. Negus SS, Mello NK, Blough BE, Baumann MH, Rothman RB . Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys . The Journal of Pharmacology and Experimental Therapeutics . 320 . 2 . 627–36 . February 2007 . 17071819 . 10.1124/jpet.106.107383 . 8326027 .