3-Deoxy-2-octulosonidase explained

3-Deoxy-2-octulosonidase
Ec Number:3.2.1.124
Cas Number:103171-48-8

3-Deoxy-2-octulosonidase (2-keto-3-deoxyoctonate hydrolase, octulosylono hydrolase, octulofuranosylono hydrolase, octulopyranosylonohydrolase) is an enzyme with systematic name capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase.[1] This enzyme catalyses the following chemical reaction

Endohydrolysis of the β-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides

The bacteriophage enzyme depolymerizes polysaccharides containing 3-deoxy-2-octulosonide in the cell wall of Escherichia coli.

Notes and References

  1. Altmann F, Kwiatkowski B, Stirm S, März L, Unger FM . A bacteriophage-associated glycanase cleaving beta-pyranosidic linkages of 3-deoxy-D-manno-2-octulosonic acid (KDO) . Biochemical and Biophysical Research Communications . 136 . 1 . 329–35 . April 1986 . 3707579 . 10.1016/0006-291x(86)90914-9 .