3-Bromopyridine Explained

3-Bromopyridine is an aryl bromide and isomer of bromopyridine with the formula C5H4BrN. It is a colorless liquid that is mainly used as a building block in organic synthesis.[1]

It participates as a substrate in many reactions associated with aryl halides, e.g., the Heck reaction[2] and Buchwald-Hartwig coupling.[3]

Notes and References

  1. 10.15227/orgsyn.081.0089. Synthesis of 3-Pyridylboronic Acid and ITS Pinacol Ester. Application of 3-Pyridylboronic Acid in Suzuki Coupling to Prepare 3-Pyridin-3-Ylquinoline. Organic Syntheses. 2005. 81. 89. Wenjie. Li. Dorian P.. Nelson. Mark S.. Jensen. R. Scott. Hoerrner. Dongwei. Cai. Robert D.. Larsen. free.
  2. 10.1021/ar50136a006. Palladium-catalyzed reactions of organic halides with olefins. 1979. Heck. Richard F.. Accounts of Chemical Research. 12. 4. 146–151.
  3. 10.1021/jo0504464. Amino Acid Promoted CuI-Catalyzed C−N Bond Formation between Aryl Halides and Amines or N-Containing Heterocycles. 2005. Zhang. Hui. Cai. Qian. Ma. Dawei. The Journal of Organic Chemistry. 70. 13. 5164–5173. 15960520.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "3-Bromopyridine".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.