3,5-Dimethylpiperidine Explained

3,5-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Two diastereomers exist: the achiral R,S isomer and the chiral R,R/S,S enantiomeric pair. 3,5-Dimethylpiperidine is a precursor to tibric acid.

The compound is typically prepared by hydrogenation of 3,5-dimethylpyridine. Both diastereomers also arise from the reduction of 3,5-dimethylpyridine with lithium triethylborohydride.[1]

References

  1. Reduction of isoquinoline and pyridine-containing heterocycles with lithium triethylborohydride (Super-Hydride). Blough, Bruce E.. Carroll. F. Ivy. Tetrahedron Letters. 1993. 34. 45. 7239–42. 10.1016/S0040-4039(00)79297-5.

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