3,3-Diethyl-2-pyrrolidinone explained

Verifiedfields:changed
Verifiedrevid:477217175
Iupac Name:3,3-Diethylpyrrolidin-2-one
Cas Number:175698-05-2
Unii:YW6BG9J9SK
Atc Prefix:none
Pubchem:9793807
Chemspiderid:7969574
Chebi:180486
Chembl:293075
C:8
H:15
N:1
O:1
Smiles:CCC1(CC)CCNC1=O
Stdinchi:1S/C8H15NO/c1-3-8(4-2)5-6-9-7(8)10/h3-6H2,1-2H3,(H,9,10)
Stdinchikey:WYPUMACPRYGQOM-UHFFFAOYSA-N

3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans.[2]

Notes and References

  1. Hill MW, Reddy PA, Covey DF, Rothman SM . Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons . The Journal of Neuroscience . 18 . 14 . 5103–11 . July 1998 . 9651194 . 6793480 . 10.1523/JNEUROSCI.18-14-05103.1998 .
  2. Evason K, Huang C, Yamben I, Covey DF, Kornfeld K . Anticonvulsant medications extend worm life-span . Science . 307 . 5707 . 258–62 . January 2005 . 15653505 . 10.1126/science.1105299 . 2005Sci...307..258E . 22154410 .