| 3′,5′-cyclic-GMP phosphodiesterase | |
| Ec Number: | 3.1.4.35 |
| Cas Number: | 9068-52-4 |
| Go Code: | 0047555 |
The enzyme 3′,5′-cyclic-GMP phosphodiesterase (EC 3.1.4.35) catalyzes the reaction
guanosine 3′,5′-cyclic phosphate + H2O
\rightleftharpoons
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is 3′,5′-cyclic-GMP 5'-nucleotidohydrolase. Other names in common use include guanosine cyclic 3',5'-phosphate phosphodiesterase, cyclic GMP phosphodiesterase, cyclic 3′,5′-GMP phosphodiesterase, cyclic guanosine 3′,5′-monophosphate phosphodiesterase, cyclic guanosine 3′,5′-phosphate phosphodiesterase, cGMP phosphodiesterase, cGMP-PDE, and cyclic guanosine 3′,5′-phosphate phosphodiesterase.
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes,,,, and .