| Incumbent: | 1989–1993 |
| Date Formed: | 1 June 1989 |
| Date Dissolved: | 25 February 1993 |
| Government Head Title: | Prime Minister |
| Government Head: | Khamtai Siphandon Kaysone Phomvihane |
| Other Government Minister Title: | Deputy Prime Minister |
| Other Government Minister: | Nouhak Phoumsavanh Phoumi Vongvichit Khamtai Siphandon Somsavat Lengsavad Sali Vongkhamsao |
| State Head Title: | President |
| State Head: | Nouhak Phoumsavanh Kaysone Phomvihane |
| Political Party: | Lao People's Revolutionary Party |
| Legislature Term: | 2nd National Assembly |
| Election: | 1989 Election of Deputies |
| Previous: | First Government |
| Successor: | Third Government |
The Second Government of the Lao People's Democratic Republic was established on 1 June 1989.
| Ministry | Minister | Took office | Left office | |
|---|---|---|---|---|
| Prime Minister | Kaysone Phomvihane | 1 June 1989 | 15 August 1991 | |
| Khamtai Siphandon | 15 August 1991 | 25 February 1993 | ||
| First Deputy Prime Minister | Nouhak Phoumsavanh | 1 June 1989 | 15 August 1991 | |
| Deputy Prime Minister | Phoumi Vongvichit | 1 June 1989 | 15 August 1991 | |
| Deputy Prime Minister | Khamtai Siphandon | 1 June 1989 | 25 February 1993 | |
| Phoun Sipaseut | 1 June 1989 | 25 February 1993 | ||
| Sali Vongkhamsao | 1 June 1989 | 23 January 1991 | ||
| Minister of Foreign Affairs | Phoun Sipaseut | 1 June 1989 | 25 February 1993 | |
| Ministry of Economics, Planning, and Finance | Sali Vongkhamsao | 1 June 1989 | 23 January 1991 | |
| Khamphoui Keoboualapha | 23 January 1991 | 15 August 1991 | ||
| Ministry of Finance | Khamsay Souphanouvong | 15 August 1991 | 25 February 1993 | |
| Minister of Interior | Asang Laoli | 1 June 1989 | 25 February 1993 | |
| Minister of Defense | Khamtai Siphandon | 1 June 1989 | 15 August 1991 | |
| Choummaly Sayasone | 15 August 1991 | 25 February 1993 | ||
| Minister of Commerce and Foreign Economic Relations | Phao Bounnaphon | 1 June 1989 | 25 February 1993 | |
| Minister of Agriculture, Forestry, Irrigation and Co-operatives | Inkonf Mahavong | 1 June 1989 | 1991 | |
| Sisavath Keobounphanh | 1991 | 25 February 1993 | ||
| Minister of Industry and Handicrafts | Soulivong Daravong | 1 June 1989 | 25 February 1993 | |
| Minister of Transport and Communications | Oudom Khattigna | 1 June 1989 | 25 February 1993 | |
| Minister of Education | Samane Vignaket | 1 June 1989 | 1991 | |
| ? | 1991 | ? | ||
| Minister of Health and Welfare | Khamkou Sounikay | 1 June 1989 | 25 February 1993 | |
| Minister of Culture | Thongsing Thammavong | 1 June 1989 | 25 February 1993 | |
| Minister of Justice | Kou Souvannamethi | 1 June 1989 | 25 February 1993 |
| Ministry | Minister | Took office | Left office |
|---|---|---|---|
| President of the Committee for Planning and Cooperation | Khamphoui Keoboualapha | 15 August 1991 | 25 February 1993 |
| Governor of the State Bank | Pany Yathotou | 1 June 1989 | 1992 |
| Bousabong Souvannavong | 1992 | 25 February 1993 |
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