2,4,5-Trimethoxyphenethylamine Explained

2,4,5-Trimethoxyphenethylamine (2C-O or 2C-OMe) or is a phenethylamine of the 2C family and was first synthesized by Jansen in 1931.^[1] It is a positional isomer of the drug mescaline (3,4,5-trimethoxy).

Chemistry

2C-O is a member of a class of chemical compounds commonly known as phenethylamines. Its full chemical name is 2-(2,4,5-trimethoxyphenyl)ethanamine; it is also known as 2,4,5-trimethoxyphenethylamine and 2,4,5-TMPEA.

Effects

Although not centrally active itself, 2C-O appeared to potentiate the action of mescaline when employed as pretreatment 45 minutes prior to the administration of mescaline.

Dangers

The toxicity of 2C-O is not known.

Law

Canada

As of October 31, 2016, 2C-O is a controlled substance (Schedule III) in Canada.^[2]

United States

2C-O is a Schedule I substance, as a positional isomer of mescaline.

United Kingdom

2C-O and all other compounds featured in PiHKAL are Class A drugs in the United Kingdom.

External links

• 2C-O Entry in PiHKAL
• TMPEA Entry in PiHKAL • info

Notes and References

1. Jansen, MPJM . 1931 . β-2: 4: 5-Trimethoxyphenylethylamine, an isomer of mescaline . Recueil des Travaux Chimiques des Pays-Bas . 50 . 4 . 291–312 . 10.1002/recl.19310500403 . 22 November 2022.
2. Web site: Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines). Public Works and Government Services Canada. Government of Canada. May 4, 2016. gazette.gc.ca.