25N-NBOMe explained

25N-NBOMe (2C-N-NBOMe, NBOMe-2C-N) is a derivative of the hallucinogen 2C-N. The pharmacological properties of 25N-NBOMe have not been described in the scientific literature, but it is believed to act in a similar manner to related compounds such as 25I-NBOMe and 25C-NBOMe, which are potent agonists at the 5HT_2A receptor.^{[1] [2]} 25N-NBOMe has been sold as a street drug and has only been described in the literature in terms of identification by forensic analysis.^{[3] [4]}

Toxicity and harm potential

Emergency treatment

Legality

United States

25N-NBOMe is illegal in Alabama.^[5]

Hungary

25N-NBOMe is illegal in Hungary.^[6]

Sweden

The Riksdag added 25N-NBOMe to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of January 16, 2015, published by Medical Products Agency (MPA) in regulation LVFS 2014:11 listed as 25N-NBOMe, and 2-(2,5-dimetoxi-4-nitrofenyl)-N-(2-metoxibensyl)etanamin.^[7]

United Kingdom

See also

• 25B-NBOMe
• 25C-NBOMe
• 25I-NBOMe
• 25TFM-NBOMe

Notes and References

1. Hansen . M. . Phonekeo . K. . Paine . J. S. . Leth-Petersen . S. . Begtrup . M. . Bräuner-Osborne . H. . Kristensen . J. L. . 10.1021/cn400216u . Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT_2A/2C Agonists . ACS Chemical Neuroscience . 5 . 3 . 243–9 . 2014 . 24397362. 3963123.
2. Hansen M . Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain. . Ph.D. . University of Copenhagen . 2010-12-16 . 10.13140/RG.2.2.33671.14245.
3. Casale. John F.. Hays, Patrick A.. Characterization of Eleven 2,5-Dimethoxy-N-(2-methoxybenzyl)phenethylamine (NBOMe) Derivatives and Differentiation from their 3- and 4-Methoxybenzyl Analogues - Part I. Microgram Journal. 2012. 9. 2. 84–109. 14 January 2014.
4. Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products . Uchiyama N, Shimokawa Y, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y . Forensic Toxicology . 2014 . 32 . 1 . 105–115 . 10.1007/s11419-013-0217-2. 32599561 .
5. https://legiscan.com/AL/text/SB333/id/988417/Alabama-2014-SB333-Enrolled.pdf Alabama Senate Bill SB 333: Controlled Substances
6. http://www.daath.hu/incoming/designer_jogi_lista_20150903_BSZKI_Daath_kieg.pdf A Daath.hu kiegészítése a BSZKI "designer jogi listáján" nem szereplő, de az UP jegyzék 1.-4. szerkezeti leírásainak megfelelő, illetve az 5. felsorolásában szereplő néhány anyagról
7. Web site: Archived copy . 2017-04-21 . https://web.archive.org/web/20150316055728/http://www.lakemedelsverket.se/upload/lvfs/LVFS_2014_11.pdf . 2015-03-16 . dead .