23S rRNA pseudouridine2605 synthase explained

23S rRNA pseudouridine^2605 synthase
Ec Number:	5.4.99.22

23S rRNA pseudouridine²⁶⁰⁵ synthase (RluB, YciL) is an enzyme with systematic name 23S rRNA-uridine²⁶⁰⁵ uracil mutase.^{[1] [2]} This enzyme catalyses the following chemical reaction

23S rRNA uridine²⁶⁰⁵

\rightleftharpoons 23S rRNA pseudouridine²⁶⁰⁵

Pseudouridine synthase RluB converts uridine²⁶⁰⁵ of 23S rRNA to pseudouridine.

Notes and References

1. Del Campo M, Kaya Y, Ofengand J . Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli . RNA . 7 . 11 . 1603–15 . November 2001 . 11720289 . 1370202 .
2. Jiang M, Sullivan SM, Walker AK, Strahler JR, Andrews PC, Maddock JR . Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques . Journal of Bacteriology . 189 . 9 . 3434–44 . May 2007 . 17337586 . 1855874 . 10.1128/jb.00090-07 .