23S rRNA (cytidine2498-2'-O)-methyltransferase explained

23S rRNA (cytidine2498-2'-O)-methyltransferase
Ec Number:	2.1.1.186

23S rRNA (cytidine²⁴⁹⁸-2'-O)-methyltransferase (YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine²⁴⁹⁸ in 23S rRNA

\rightleftharpoons S-adenosyl-L-homocysteine + 2'-O-methylcytidine²⁴⁹⁸ in 23S rRNA

Notes and References

1. Purta E, O'Connor M, Bujnicki JM, Douthwaite S . YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA . Molecular Microbiology . 72 . 5 . 1147–58 . June 2009 . 19400805 . 10.1111/j.1365-2958.2009.06709.x . free .