21S rRNA pseudouridine2819 synthase explained

21S rRNA pseudouridine^2819 synthase
Ec Number:	5.4.99.43

21S rRNA pseudouridine²⁸¹⁹ synthase (Pus5p) is an enzyme with systematic name 21S rRNA-uridine²⁸¹⁹ uracil mutase.^[1] This enzyme catalyses the following chemical reaction

21S rRNA uridine²⁸¹⁹

\rightleftharpoons 21S rRNA pseudouridine²⁸¹⁹

The enzyme specifically acts on uridine²⁸¹⁹ in 21S rRNA.

Notes and References

1. Ansmant I, Massenet S, Grosjean H, Motorin Y, Branlant C . Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA . Nucleic Acids Research . 28 . 9 . 1941–6 . May 2000 . 10756195 . 103309 . 10.1093/nar/28.9.1941 .