| Team: | DC Defenders |
| Year: | 2025 |
| Record: | 0–0 |
| Coach: | Reggie Barlow |
| General Manager: | Von Hutchins |
| Owner: | Alpha Acquico, LLC |
| Stadium: | Audi Field |
The 2025 DC Defenders season will be the fourth season for the DC Defenders as a professional American football franchise and the second season in the United Football League (UFL).[1] The Defenders will play their home games at Audi Field and will be led by third-year head coach Reggie Barlow.
Listed below are the Defenders' opponents for 2025. Exact dates and times will be announced at the end of 2024.
| Category | Home | Away | |
|---|---|---|---|
| Conference opponents (XFL) | Arlington Renegades San Antonio Brahmas St. Louis Battlehawks | ||
| Interconference opponents (USFL) | Houston Roughnecks Michigan Panthers | ||