See main article: article and 2024 Winston-Salem Open.
Lorenzo Sonego won the singles title at the 2024 Winston-Salem Open, defeating Alex Michelsen in the final, 6–0, 6–3. He did not drop a set en route to his fourth ATP Tour title and first since 2022.
Sebastián Báez was the defending champion,[1] but lost to Borna Ćorić in the second round.
All seeds received a bye into the second round.