| Date: | 21 – 27 October |
| Edition: | 1st |
| Surface: | Hard (indoor) |
| Location: | Sioux Falls, South Dakota, United States |
| Champs: | Borna Gojo |
| Champd: |  Liam Draxl / Cleeve Harper |
The 2024 Sioux Falls Challenger was a professional tennis tournament played on indoor hard courts. It was the first edition of the tournament which was part of the 2024 ATP Challenger Tour. It took place in Sioux Falls, South Dakota, United States between 21 and 27 October 2024.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 United States | Christopher Eubanks | 120 | 1 | |
| United States | Mitchell Krueger | 149 | 2 | |
| United States | Zachary Svajda | 163 | 3 | |
 Poland | Maks Kaśnikowski | 171 | 4 | |
 Kazakhstan | Dmitry Popko | 173 | 5 | |
| United States | Patrick Kypson | 177 | 6 | |
| United States | Nishesh Basavareddy | 195 | 7 | |
| United States | Brandon Holt | 196 | 8 |
The following players received wildcards into the singles main draw:
Kyle Edmund Matthew Forbes Colton SmithThe following players received entry into the singles main draw as special exempts:
The following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Antoine Ghibaudo Andres Martin Keegan Smith Cooper WoestendickThe following player received entry as a lucky loser:
See main article: article and 2024 Sioux Falls Challenger – Singles.
Colton Smith 6–1, 7–5.See main article: article and 2024 Sioux Falls Challenger – Doubles.
Liam Draxl / Cleeve Harper def. Ryan Seggerman / Patrik Trhac 7–5, 6–3.