| Champ: |  Nadia Podoroska |
| Runner: |  Francesca Jones |
| Score: | 6–1, 6–2 |
See main article: 2024 San Luis Open Challenger.
Elisabetta Cocciaretto was the defending champion,[1] but lost in the semifinals to Nadia Podoroska.
Podoroska won the title after defeating Francesca Jones 6–1, 6–2 in the final.