The 2024 San Luis Open was a professional tennis tournament played on outdoor clay courts. It was the 29th edition of the tournament for the men which was part of the 2024 ATP Challenger Tour[1] and 2nd edition for the women which was part of the 2024 WTA 125 tournaments.[2] It took place at the Club Deportivo Potosino in San Luis Potosí, Mexico between 25 and 31 March 2024.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Argentina | Thiago Agustín Tirante | 99 | 1 | |
 Australia | James Duckworth | 109 | 2 | |
| Tomás Barrios Vera | 111 | 3 | ||
| Valentin Vacherot | 146 | 4 | ||
 United States | Denis Kudla | 163 | 5 | |
 France | Giovanni Mpetshi Perricard | 165 | 6 | |
| Australia | Marc Polmans | 167 | 7 | |
 United Kingdom | Oliver Crawford | 203 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
Gerard Campana Lee
Dominik PalánThe following players received entry from the qualifying draw:
Andrés Andrade
Roberto Cid Subervi Christian Langmo
Nicolás Mejía
Beibit Zhukayev| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Tatjana Maria | 48 | 1 | ||
 Italy | Elisabetta Cocciaretto | 51 | 2 | |
 Spain | Sara Sorribes Tormo | 52 | 3 | |
| Argentina | Nadia Podoroska | 78 | 4 | |
| Erika Andreeva | 94 | 5 | ||
| United States | Hailey Baptiste | 96 | 6 | |
| France | Alizé Cornet | 99 | 7 | |
| Argentina | María Lourdes Carlé | 101 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Nuria Brancaccio
Jéssica Hinojosa Gómez
Anca Todoni
You Xiaodi| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| United States | Angela Kulikov | France | Elixane Lechemia | 182 | 1 | |
| Julia Lohoff | Conny Perrin | 215 | 2 | |||
| Romania | Irina Bara | Dalila Jakupović | 240 | 3 | ||
| United States | Hailey Baptiste | United States | Whitney Osuigwe | 256 | 4 |
See main article: 2024 San Luis Open Challenger – Men's singles.
Nicolás Mejía def. Matías Soto 6–1, 5–7, 6–2.See main article: 2024 San Luis Open Challenger – Women's singles.
Nadia Podoroska def. Francesca Jones 6–1, 6–2.See main article: 2024 San Luis Open Challenger – Men's doubles.
Rithvik Choudary Bollipalli / Niki Kaliyanda Poonacha def. Antoine Bellier / Marc-Andrea Hüsler 6–3, 6–2.See main article: 2024 San Luis Open Challenger – Women's doubles.
Anna Bondár / Tamara Zidanšek def. 
Laura Pigossi / 
Katarzyna Piter, Walkover