| Date: | 1 – 7 April |
| Edition: | 3rd |
| Surface: | Clay |
| Location: | Mexico City, Mexico |
| Champs: |  Thiago Agustín Tirante |
| Champd: |  Ryan Seggerman / Patrik Trhac |
The 2024 Mexico City Open was a professional tennis tournament played on clay courts. It was the third edition of the tournament which was part of the 2024 ATP Challenger Tour. It took place in Mexico City, Mexico between 1 and 7 April 2024.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Argentina | Thiago Agustín Tirante | 99 | 1 | |
 Australia | Adam Walton | 150 | 2 | |
 France | Giovanni Mpetshi Perricard | 165 | 3 | |
| Australia | Marc Polmans | 167 | 4 | |
 Kazakhstan | Beibit Zhukayev | 191 | 5 | |
 United Kingdom | Oliver Crawford | 203 | 6 | |
| Australia | Omar Jasika | 208 | 7 | |
| Marc-Andrea Hüsler | 209 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as special exempts:
The following players received entry from the qualifying draw:
Alafia Ayeni
Gerard Campana Lee
Alex Hernández
Skander MansouriSee main article: 2024 Mexico City Open – Singles.
Thiago Agustín Tirante def. 
Alexis Galarneau 6–1, 6–3.See main article: 2024 Mexico City Open – Doubles.
Ryan Seggerman / Patrik Trhac def. Tristan Schoolkate / Adam Walton 5–7, 6–4, [10–5].