| Date: | 2–7 September |
| Edition: | 4th |
| Draw: | 32S / 8D |
| Category: | WTA 125 |
| Location: | Guadalajara, Mexico |
| Venue: | Panamerican Tennis Center |
| Surface: | Hard |
| Champs: | Kamilla Rakhimova |
| Champd: |  Katarzyna Piter /  Fanny Stollár |
| Before Year: | 2022 |
| Before Name: | Abierto Zapopan |
| Main Name: | Abierto Zapopan |
The 2024 Guadalajara 125 Open was a professional tennis tournament played on outdoor hard courts. It was the 4th edition of the tournament and part of the 2024 WTA 125 tournaments (downgraded from WTA 250 status for the two previous editions). It took place in Guadalajara, Mexico from 2 to 7 September 2024.[1]
See main article: 2024 Guadalajara 125 Open – Singles.
See main article: 2024 Guadalajara 125 Open – Doubles.
Katarzyna Piter / Fanny Stollár def. 
Angelica Moratelli / 
Sabrina Santamaria, 6–4, 7–5| Country | Player | Rank¹ | Seed | |
|---|---|---|---|---|
 Slovakia | Anna Karolína Schmiedlová | 87 | 1 | |
| Italy | Martina Trevisan | 90 | 2 | |
 Mexico | Renata Zarazúa | 92 | 3 | |
| Tatjana Maria | 99 | 4 | ||
| Kamilla Rakhimova | 104 | 5 | ||
| United States | Emina Bektas | 116 | 6 | |
| United States | ||||
 Argentina | Julia Riera | 120 | 8 | |
 Australia | Maya Joint | 135 | 9 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Alycia Parks → replaced by 
Aleksandra Krunić| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Italy | Angelica Moratelli | United States | Sabrina Santamaria | 165 | 1 | |
| Poland | Katarzyna Piter | Hungary | Fanny Stollár | 182 | 2 |
The following pair received a wildcard into the doubles main draw:
The following pair received entry as alternates:
Olivia Gadecki / Julia Riera → replaced by Kimberly Birrell / Alex Eala
