| Mode: | Women's basketball |
| Year: | 2024–25 |
| Prev Year: | 2023–24 |
| Next Year: | 2025–26 |
| Team: | Southeastern Louisiana Lady Lions |
| Conference: | Southland Conference |
| Short Conf: | Southland |
| Record: | 3–1 |
| Conf Record: | 0–0 |
| Hc Year: | 8th |
| Asst Coach1: | Kenneth Lee, Jr. |
| Asst Coach2: | Ronneka Robertson |
| Asst Coach3: | Aja Ochie |
The 2024–25 Southeastern Louisiana Lady Lions basketball team will represent Southeastern Louisiana University in the 2024–25 NCAA Division I women's basketball season. The Lady Lions will be led by eighth-year head coach Ayla Guzzardo, and will play their home games at Pride Roofing University Center as members of the Southland Conference.
See main article: 2023–24 Southeastern Louisiana Lady Lions basketball team. The Lady Lions finished the 2023–24 season 19–12 overall, 14–4 in Southland play to finish tied for second place. With a first round bye, they defeated Nicholls in the second round of the Southland women's tournament. Their season ended when they were defeated by Texas A&M–Corpus Christi in the semi-finals.
Home games are broadcast on ESPN+.
The Southland Conference released its preseason poll on October 17, 2024. Receiving 213 overall votes and five first-place votes, the Lady Lions were picked to finish second in the conference.[1]
| 1 | Lamar | 236 (19) |
| 2 | Southeastern Louisiana | 213 (5) |
| 3 | Texas A&M–Corpus Christi | 200 |
| 4 | Stephen F. Austin | 193 |
| 5 | Incarnate Word | 149 |
| 6 | Texas A&M–Commerce | 112 |
| 7 | Nicholls | 108 |
| 8 | New Orleans | 109 |
| 9 | UT Rio Grande Valley | 92 |
| 10 | Northwestern State | 67 |
| 11 | McNeese | 61 |
| 12 | Houston Christian | 51 |
Junior forward Lexi Alexander was selected to the Preseason All-Conference first team. Senior and junior guards Taylor Bell and Jalencia Pierre were selected to the second team.[1]
|-!colspan=9 style=| Exhibition|-!colspan=9 style=| Non-conference regular season|-!colspan=9 style=| Southland Conference regular season|-!colspan=9 style=|2025 Jersey Mike's Subs Southland Conference TournamentSource:[2] [3]