| Date: | 8–14 May 2023 |
| Edition: | 12th |
| Surface: | Clay / Outdoor |
| Location: | Trnava, Slovakia |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $100,000 |
| Champs: |  Yanina Wickmayer |
| Champd: | Amina Anshba /  Anastasia Dețiuc |
| Before Year: | 2019 |
The 2023 Empire Slovak Open was a professional tennis tournament played on outdoor clay courts. It was the twelfth edition of the tournament, which was part of the 2023 ITF Women's World Tennis Tour. It took place in Trnava, Slovakia, between 8 and 14 May 2023.[1]
See main article: 2023 Empire Slovak Open – Singles.
Yanina Wickmayer def. Greet Minnen, 6–0, 6–3See main article: 2023 Empire Slovak Open – Doubles.
Anastasia Dețiuc def. 
Estelle Cascino / Suzan Lamens, 6–3, 4–6, [10–4]| Country | Player | Rank | Seed | |
|---|---|---|---|---|
 Slovakia | Anna Karolína Schmiedlová | 96 | 1 | |
| Viktorija Golubic | 108 | 2 | ||
 China | Yuan Yue | 116 | 3 | |
| Belgium | Greet Minnen | 173 | 4 | |
 Japan | Mai Hontama | 180 | 5 | |
 Serbia | Natalija Stevanović | 186 | 6 | |
| Belgium | Yanina Wickmayer | 188 | 7 | |
| France | Chloé Paquet | 192 | 8 |
The following players received wildcards into the singles main draw:
Kristína Kučová Ela Pláteníková Radka ZelníčkováThe following player received entry from a junior exempt:
The following players received entry from the qualifying draw:
Ilona Georgiana Ghioroaie Aneta Kučmová Eszter Méri Ivana Šebestová Anna Sisková Tereza SmitkováThe following players received entry as lucky losers:
Irina Balus Sofia Milatová