| Date: | 1–7 May 2023 |
| Edition: | 30th (men) 18th (women) |
| Surface: | Clay / Outdoor |
| Location: | Prague, Czech Republic |
| Category: | ATP Challenger Tour ITF Women's World Tennis Tour |
| Champms: | Dominic Stricker |
| Champmd: |  Petr Nouza / Andrew Paulson |
| Champws: | Darja Semeņistaja |
| Champwd: |  Maja Chwalińska / Jesika Malečková |
| Before Name: | I.ČLTK Prague Open |
| Main Name: | I.ČLTK Prague Open |
The 2023 Advantage Cars Prague Open was a tournament played on outdoor clay. It was the 30th edition for men and 18th for women, which were respectively part of the 2023 ATP Challenger Tour and the 2023 ITF Women's World Tennis Tour. It took place in Prague, Czech Republic between 1 and 7 May 2023.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Serbia | Filip Krajinović | 79 | 1 | |
 Moldova, Republic of | Radu Albot | 103 | 2 | |
 Argentina | Juan Manuel Cerúndolo | 104 | 3 | |
 France | Hugo Gaston | 106 | 4 | |
 Hungary | Zsombor Piros | 118 | 5 | |
| Czech Republic | Tomáš Macháč | 123 | 6 | |
| Dominic Stricker | 129 | 7 | ||
 Austria | Sebastian Ofner | 130 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as special exempts:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Hungary | Réka Luca Jani | 131 | 1 | |
 Australia | Priscilla Hon | 163 | 2 | |
 Italy | Nuria Brancaccio | 170 | 3 | |
 Spain | Jéssica Bouzas Maneiro | 182 | 4 | |
 Mexico | Fernanda Contreras | 189 | 5 | |
| Czech Republic | Barbora Palicová | 202 | 6 | |
| Céline Naef | 210 | 7 | ||
| Darja Semeņistaja | 215 | 8 |
The following players received wildcards into the singles main draw:
Victoria Bervid Lucie Havlíčková Dominika Šalková Tereza ValentováThe following player received entry using a special ranking:
The following player received entry as a special exempt:
The following player received entry as a junior exempt:
The following players received entry from the qualifying draw:
Ilona Georgiana Ghioroaie
Anastasia Kulikova
Katarína Kužmová Ivana Šebestová
Valeriya Strakhova
Karman ThandiThe following player received entry as a lucky loser:
See main article: 2023 Advantage Cars Prague Open – Men's singles.
Sebastian Ofner 7–6(9–7), 6–3.See main article: 2023 Advantage Cars Prague Open – Men's doubles.
Petr Nouza / Andrew Paulson def. Jiří Barnat / Jan Hrazdil 6–4, 6–3.See main article: 2023 Advantage Cars Prague Open – Women's singles.
Jéssica Bouzas Maneiro, 2–6, 6–3, 6–4See main article: 2023 Advantage Cars Prague Open – Women's doubles.
Maja Chwalińska / Jesika Malečková def. Aneta Kučmová / Kaylah McPhee, 6–0, 7–6(7–5)
