| Club: | UC Sampdoria |
| Season: | 2023–24 |
| Manager: | Andrea Pirlo |
| Stadium: | Stadio Luigi Ferraris |
| League: | Serie B |
| League Result: | 7th |
| Cup1: | Coppa Italia |
| Cup1 Result: | Round of 32 |
| League Topscorer: | Manuel De Luca (10) |
| Season Topscorer: | Manuel De Luca (10) |
| Prevseason: | 2022–23 |
| Nextseason: | 2024–25 |
The 2023–24 season was UC Sampdoria's 78th season in existence and the club's first season in the second division of Italian football. In addition to the domestic league, UC Sampdoria participated in this season's edition of the Coppa Italia. The season covers the period from 1 July 2023 to 30 June 2024.
| Player | Transferred from | Fee | Date | Source |
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| Player | Transferred to | Fee | Date | Source |
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See main article: 2023–24 Serie B.
The league fixtures were unveiled on 11 July 2023.[2]
See main article: 2023–24 Coppa Italia.