The 2022 Women's Six Nations Championship was the 21st Women's Six Nations Championship, an annual rugby union competition contested by the national teams of England, France, Ireland, Italy, Scotland and Wales. England were the defending champions, having won a COVID shortened version of the tournament in 2021. There was no limit on the number of players each team may call up to play in the competition.
Note: Number of caps are indicated as of the first match of the tournament (26 March 2022).
Head coach: Simon Middleton
On 7 March Simon Middleton announced England's 40 player squad for the tournament[1] [2]
Head coach: 
Annick Hayraud
On 14 March 2022 Annick Hayraud announced their 35 player squad for the tournament.[3] [4]
On 29 March Céline Ferer, Maïlys Traoré and Safi N'Diaye were all added to the squad to face Ireland[5]
Caroline Boujard was added to the squad prior to the fourth round match against Wales.
Head coach: Greg McWilliams
On 3 March 2022 Greg McWilliams announced his 38 player squad for the tournament.[6] [7]
On 21 March Nichola Fryday was named captain for the tournament.[8]
On 19 April 2022 Laura Feely, Laura Sheehan, Mary Healy, Shannon Touhey, Sene Naoupu, Niamh Byrne and Alice O'Dowd were all called up to the squad.[9]
Head coach: 
Andrea Di Giandomenico
On 14 March 2022 Andrea Di Giandomenico announced his squad for the championship.[10] [11]
Due to a COVID-19 outbreak in the Italy squad Federica Cipolla was added to the squad for the Round 3 game against Ireland.[12]
| Player | Position | Caps | Club/Province | |
|---|---|---|---|---|
| Ilaria Arrighetti | Flanker | 51 | Stade Rennais | |
| Sara Barattin | Scrumhalf | 101 | Villorba Rugby | |
| Melissa Bettoni | Hooker | 64 | Stade Rennais | |
| Francesca Barro | Prop | 0 | Valsugana Rugby Padova | |
| Beatrice Capomaggi | Centre | 4 | Villorba Rugby | |
| Federica Cipolla | Wing | 0 | Villorba Rugby | |
| Alyssa D'Inca' | Centre | 4 | Villorba Rugby | |
| Giordana Duca | Lock | 24 | Valsugana Rugby Padova | |
| Valeria Fedrighi | Lock | 28 | Stade Toulousain | |
| Alessandra Frangipani | Flanker | 0 | Villorba Rugby | |
| Giada Franco | Flanker | 21 | Rugby Colorno | |
| Manuela Furlan (c) | Fullback | 81 | Villorba Rugby | |
| Lucia Gai | Prop | 76 | Valsugana Rugby Padova | |
| Elisa Giordano | Flanker | 49 | Valsugana Rugby Padova | |
| Francesca Granzotto | Centre / Wing | 0 | Unione Rugby Capitolina | |
| Isabella Locatelli | Flanker | 28 | Rugby Colorno | |
| Veronica Madia | Fullback | 25 | Rugby Colorno | |
| Maria Magatti | Centre | 38 | CUS Milano Rugby | |
| Alessia Margotti | Prop | 0 | Valsugana Rugby Padova | |
| Gaia Maris | Prop | 6 | Valsugana Rugby Padova | |
| Michela Merlo | Prop | 11 | Rugby Colorno | |
| Aura Muzzo | Wing | 20 | Villorba Rugby | |
| Vittoria Ostuni Minuzzi | Fullback | 9 | Valsugana Rugby Padova | |
| Beatrice Rigoni | Wing | 49 | Valsugana Rugby Padova | |
| Francesca Sberna | Flanker | 6 | Rugby Calvisano | |
| Sara Seye | Prop | 2 | Rugby Calvisano | |
| Michela Sillari | Centre | 63 | Valsugana Rugby Padova | |
| Emanuela Stecca | Hooker | 0 | Villorba Rugby | |
| Sofia Stefan | Scrumhalf | 62 | Valsugana Rugby Padova | |
| Sara Tounesi | Lock | 18 | ASM Romagnat | |
| Silvia Turani | Hooker | 16 | Rugby Colorno | |
| Emma Stevanin | Prop | 0 | Valsugana Rugby Padova | |
| Vittoria Vecchini | Hooker | 3 | Valsugana Rugby Padova | |
| Beatrice Veronese | Flanker | 7 | Valsugana Rugby Padova |
Head coach: Bryan Easson
On 15 March 2022 Scotland head coach Bryan Easson announced his team for the 2022 championship.[13] [14]
Panashe Muzambe was added to the squad prior to Scotland's second-round game against Wales.[15]
Head coach: Ioan Cunningham
On 17 March 2022 Cunningham named their 37 player squad for the championship.[16] [17]