| Date: | 8–14 August 2022 |
| Edition: | 3rd |
| Surface: | Hard |
| Location: | Concord, United States |
| Venue: | The Thoreau Club |
| Category: | WTA 125 |
| Prize Money: | $115,000 |
| Champs: |  CoCo Vandeweghe |
| Champd: | Varvara Flink / CoCo Vandeweghe |
The 2022 Thoreau Tennis Open was a professional tennis tournament played on outdoor hard courts. It was the third edition of the tournament which was part of the 2022 WTA 125 tournaments. It took place at The Thoreau Club in Concord, Massachusetts between 8 and 14 August 2022.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Clara Tauson | 49 | 1 | ||
| United States | Bernarda Pera | 58 | 2 | |
| Varvara Gracheva | 63 | 3 | ||
 Poland | Magdalena Fręch | 82 | 4 | |
| Viktorija Golubic | 92 | 5 | ||
 China | ||||
 Belgium | Greet Minnen | 99 | 7 | |
| Kamilla Rakhimova | 107 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw through protected ranking:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Caty McNally
Ekaterine Gorgodze → replaced by Varvara Flink
Renata Zarazúa Mariam Bolkvadze Ann Li → replaced by 
Astra Sharma
Daria Snigur → replaced by Wang Qiang Wang Xiyu → replaced by 
Moyuka Uchijima
Karolína Muchová (wrist injury)| Country | Player | Country | Player | Rank† | Seed | |
|---|---|---|---|---|---|---|
| Georgia | Natela Dzalamidze | Kamilla Rakhimova | 132 | 1 | ||
| Amina Anshba | Yana Sizikova | 184 | 2 | |||
| Anna Blinkova | Belgium | Greet Minnen | 184 | 3 | ||
| Australia | Astra Sharma | Aldila Sutjiadi | 190 | 4 |
Sophie Chang / Angela Kulikov → replaced by Lidziya Marozava / Kateryna Volodko Caty McNally → replaced by Alycia Parks / Renata Zarazúa
Peangtarn Plipuech / Jessy Rompies → replaced by Peangtarn Plipuech / Moyuka UchijimaSee main article: 2022 Thoreau Tennis Open – Singles.
CoCo Vandeweghe def. Bernarda Pera 6–3, 5–7, 6–4See main article: 2022 Thoreau Tennis Open – Doubles.
CoCo Vandeweghe def. Peangtarn Plipuech / Moyuka Uchijima 6–3, 7–6(7–3)