| Year: | 2022 |
| Team: | South Dakota Coyotes |
| Sport: | football |
| Conference: | Missouri Valley Football Conference |
| Short Conf: | MVFC |
| Record: | 3–8 |
| Conf Record: | 2–6 |
| Head Coach: | Bob Nielson |
| Hc Year: | 7th |
| Off Coach: | Ted Schlafke |
| Oc Year: | 5th |
| Def Coach: | Travis Johansen |
| Dc Year: | 4th |
| Stadium: | DakotaDome |
The 2022 South Dakota Coyotes football team represented the University of South Dakota in the 2022 NCAA Division I FCS football season. The Coyotes competed as members of the Missouri Valley Football Conference and were led by seventh-year head coach Bob Nielson. They played their home games at the DakotaDome in Vermillion, South Dakota.
See also: 2022 Kansas State Wildcats football team.
South Dakota did not hold up against Kansas State, failing to score the entire game. South Dakota gave up a blocked punt that the Wildcats turned into a touchdown, couldn't stop what was called an "impressive" ground game, and gave up a touchdown in the first ten seconds. South Dakota did hold Kansas State to just 96 passing yards. Kansas State won the game 34-0.[3]See also: 2022 Montana Grizzlies football team.
See also: 2022 Cal Poly Mustangs football team.
See also: 2022 North Dakota State Bison football team.
See also: 2022 South Dakota State Jackrabbits football team and South Dakota–South Dakota State football rivalry.
See also: 2022 Illinois State Redbirds football team.
See also: 2022 Southern Illinois Salukis football team.
See also: 2022 Youngstown State Penguins football team.
See also: 2022 Missouri State Bears football team.
See also: 2022 North Dakota Fighting Hawks football team and Sitting Bull Trophy.
See also: 2022 Northern Iowa Panthers football team.