See main article: 2022 San Diego Open.
Coco Gauff and Jessica Pegula defeated Gabriela Dabrowski and Giuliana Olmos in the final, 1–6, 7–5, [10–4] to win the women's doubles tennis title at the 2022 San Diego Open.
This was the first WTA Tour-level event to be held in the San Diego area since 2013.[1]