| Date: | 24–30 January |
| Edition: | 13th |
| Surface: | Hard (indoor) |
| Location: | Quimper, France |
| Champs: |  Vasek Pospisil |
| Champd: |  Albano Olivetti /  David Vega Hernández |
| Before Name: | Open Quimper Bretagne II |
The 2022 Open Quimper Bretagne was a professional tennis tournament played on hard courts. It was the thirteenth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Quimper, France between 24 and 30 January 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Henri Laaksonen | 91 | 1 | ||
| France | Pierre-Hugues Herbert | 112 | 2 | |
 Austria | Dennis Novak | 118 | 3 | |
| France | Gilles Simon | 123 | 4 | |
| Canada | Vasek Pospisil | 138 | 5 | |
| João Sousa | 140 | 6 | ||
 Czech Republic | Jiří Lehečka | 142 | 7 | |
 Russian Federation | Roman Safiullin | 149 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
See main article: 2022 Open Quimper Bretagne – Singles.
Vasek Pospisil def. Grégoire Barrère 6–4, 3–6, 6–1.See main article: 2022 Open Quimper Bretagne – Doubles.
Albano Olivetti / David Vega Hernández def. Sander Arends / David Pel 3–6, 6–4, [10–8].
