| Date: | 26 September–2 October 2022 |
| Edition: | 1st |
| Surface: | Clay / Outdoor |
| Location: | San Sebastián, Spain |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Julia Grabher |
| Champd: |  Aliona Bolsova /  Katarina Zavatska |
The 2022 Open Internacional de San Sebastián was a professional tennis tournament played on outdoor clay courts. It was the first edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in San Sebastián, Spain between 26 September and 2 October 2022.[1]
See main article: 2022 Open Internacional de San Sebastián – Singles.
Julia Grabher def. Aliona Bolsova, 6–3, 7–6(7–3)See main article: 2022 Open Internacional de San Sebastián – Doubles.
Aliona Bolsova / Katarina Zavatska def. Ángela Fita Boluda / Guiomar Maristany, 1–2, ret.| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Austria | Julia Grabher | 99 | 1 | |
 France | Clara Burel | 103 | 2 | |
| Elina Avanesyan | 129 | 3 | ||
 Georgia | Ekaterine Gorgodze | 162 | 4 | |
 Andorra | Victoria Jiménez Kasintseva | 186 | 5 | |
 Czech Republic | Brenda Fruhvirtová | 195 | 6 | |
 Cyprus | Raluca Șerban | 197 | 7 | |
| Austria | Sinja Kraus | 201 | 8 |
The following players received wildcards into the singles main draw:
Lucía Cortez Llorca Victoria Jiménez Kasintseva Carlota Martínez Círez Ane Mintegi del OlmoThe following players received entry into the singles main draw using a protected ranking:
The following players received entry from the qualifying draw:
Nahia Berecoechea
Oana Gavrilă Nadiya Kolb Amandine MonnotThe following player received entry as a lucky loser:
Noelia Bouzó Zanotti