| Date: | 5 – 11 December |
| Edition: | 2nd |
| Draw: | 32S / 8D |
| Category: | WTA 125 |
| Location: | Angers, France |
| Venue: | Arena Loire |
| Surface: | Hard (indoor) |
| Prize Money: | $115,000 |
| Champs: |  Alycia Parks |
| Champd: | Alycia Parks /  Zhang Shuai |
The 2022 Open P2I Angers Arena Loire was a professional tennis tournament played on indoor hard courts. It was the 2nd edition of the tournament and part of the 2022 WTA 125 tournaments season, offering a total of $115,000 in prize money. It took place in Angers, France from 5 to 11 December 2022.[1]
See main article: 2022 Open Angers Arena Loire – Singles.
Alycia Parks def. Anna-Lena Friedsam 6–4, 4–6, 6–4See main article: 2022 Open Angers Arena Loire – Doubles.
Alycia Parks / Zhang Shuai def. 
Miriam Kolodziejová / Markéta Vondroušová 6–2, 6–2| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| China | Zhang Shuai | 24 | 1 | |
 Ukraine | Anhelina Kalinina | 53 | 2 | |
 Belgium | Alison Van Uytvanck | 55 | 3 | |
| Tatjana Maria | 70 | 4 | ||
| Tamara Korpatsch | 74 | 5 | ||
| Anna Blinkova | 80 | 6 | ||
| Viktoriya Tomova | 90 | 7 | ||
| Varvara Gracheva | 95 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry into the singles main draw through protected ranking:
The following players received entry from the qualifying draw:
Émeline Dartron Magali Kempen Greet MinnenThe following players received entry as lucky loser:
Yanina Wickmayer Hina Inoue
Jodie Burrage → replaced by Anna-Lena Friedsam Léolia Jeanjean → replaced by 
Pemra Özgen Linda Nosková → replaced by 
Jaqueline Cristian
Nuria Párrizas Díaz → replaced by Katarina Zavatska| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| United States | Alycia Parks | China | Zhang Shuai | 98 | 1 | |
 Georgia | Natela Dzalamidze | Alexandra Panova | 120 | 2 |
The following pair received a wildcard into the doubles main draw: