| Gender: | Women's |
| Year: | 2022 |
| Dates: | May 13–29, 2022 |
| Teams: | 29 |
| Finalsfield: | Homewood Field |
| Finalscity: | Baltimore, MD |
| Titlecount: | 3rd |
| Gamecount: | 5th |
| Semifinal1: | Northwestern |
| Finalfourcount1: | 13th |
| Semifinal2: | Maryland |
| Finalfourcount2: | 28th |
| Coachcount: | 3rd |
| Mop: | Sam Geiersbach |
| Mopteam: | North Carolina |
The 2022 NCAA Division I Women's Lacrosse Championship was the 40th annual single-elimination tournament to determine the national champion of Division I NCAA women's college lacrosse. The semifinal and championship rounds will be played at Homewood Field in Baltimore, MD from May 27–29, 2022.[1] All other rounds will be played at campus sites, usually at the home field of the higher-seeded team, from May 13–19.
All NCAA Division I women's lacrosse programs were eligible for this championship, and a total of 29 teams were invited to participate. 15 teams qualified automatically by winning their conference tournaments, while the remaining 14 teams qualified at-large based on their regular season records.[2]
| Seed | School | Conference | Berth Type | RPI[3] | Record |
|---|---|---|---|---|---|
| 1 | North Carolina | ACC | Automatic | 1 | 18–0 |
| 2 | Maryland | Big Ten | Automatic | 2 | 17–1 |
| 3 | Boston College | ACC | At-large | 3 | 16–3 |
| 4 | Northwestern | Big Ten | At-large | 4 | 13–4 |
| 5 | Syracuse | ACC | At-large | 6 | 13–5 |
| 6 | Loyola (MD) | Patriot | Automatic | 10 | 18–1 |
| 7 | Florida | American | Automatic | 5 | 15–4 |
| 8 | Stony Brook | America East | At-large | 8 | 14–2 |
| Central Michigan | MAC | Automatic | 74 | 12–7 | |
| Denver | Big East | Automatic | 9 | 17–2 | |
| Drexel | CAA | Automatic | 37 | 12–7 | |
| Duke | ACC | At-large | 13 | 15–3 | |
| Fairfield | MAAC | Automatic | 32 | 13–6 | |
| Jacksonville | ASUN | Automatic | 21 | 13–4 | |
| James Madison | CAA | At-large | 12 | 13–4 | |
| Johns Hopkins | Big Ten | At-large | 15 | 10–8 | |
| Mercer | Big South | Automatic | 34 | 14–4 | |
| Michigan | Big Ten | At-large | 20 | 10–6 | |
| Mount St. Mary's | NEC | Automatic | 45 | 15–4 | |
| Notre Dame | ACC | At-large | 17 | 9–9 | |
| Princeton | Ivy | Automatic | 11 | 14–3 | |
| Rutgers | Big Ten | At-large | 7 | 15–4 | |
| Saint Joseph's | Atlantic 10 | Automatic | 29 | 14–6 | |
| Stanford | Pac-12 | Automatic | 26 | 12–6 | |
| UConn | Big East | At-large | 14 | 13–4 | |
| UMass | Atlantic 10 | At-large | 19 | 16–3 | |
| USC | Pac-12 | At-large | 16 | 13–4 | |
| Vermont | America East | Automatic | 33 | 14–4 | |
| Virginia | ACC | At-large | 18 | 9–9 | |