See main article: 2022 Murcia Open.
Raúl Brancaccio and Flavio Cobolli were the defending champions[1] but only Brancaccio chose to defend his title, partnering Javier Barranco Cosano. Brancaccio lost in the quarterfinals to Íñigo Cervantes and Oriol Roca Batalla.
Cervantes and Roca Batalla won the title after defeating Pedro Cachin and Martín Cuevas 6–7(4–7), 7–6(7–4), [10–7] in the final.