| Date: | 28 November – 4 December |
| Edition: | 1st |
| Surface: | Clay |
| Location: | Maspalomas, Spain |
| Champs: |  Dušan Lajović |
| Champd: |  Evan King / Reese Stalder |
The 2022 Maspalomas Challenger was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Maspalomas, Spain from 28 November to 4 December 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Serbia | Dušan Lajović | 102 | 1 | |
 Czech Republic | Vít Kopřiva | 153 | 3 | |
| Alexander Shevchenko | 156 | 4 | ||
 Belgium | Kimmer Coppejans | 199 | 5 | |
| Adrian Andreev | 207 | 6 | ||
| Czech Republic | Dalibor Svrčina | 226 | 7 | |
| Serbia | Miljan Zekić | 239 | 8 |
The following players received wildcards into the singles main draw:
Iñaki Cabrera Bello Pablo Llamas Ruiz Alejandro Moro CañasThe following player received entry into the singles main draw as an alternate:
Edoardo LavagnoThe following players received entry from the qualifying draw:
Moez Echargui Imanol López Morillo Gian Marco Moroni David Pérez Sanz
Eric VanshelboimThe following player received entry as a lucky loser:
See main article: 2022 Maspalomas Challenger – Singles.
Dušan Lajović def. 
Steven Diez 6–1, 6–4.See main article: 2022 Maspalomas Challenger – Doubles.
Evan King / Reese Stalder def. Marco Bortolotti / Sergio Martos Gornés 6–3, 5–7, [11–9].