| Date: | 28 November – 4 December |
| Edition: | 5th |
| Surface: | Clay |
| Location: | Maia, Portugal |
| Champs: |  Luca Van Assche |
| Champd: |  Julian Cash / Henry Patten |
| Before Name: | Maia Challenger II |
The 2022 Maia Challenger was a professional tennis tournament played on clay courts. It was the fifth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Maia, Portugal from 28 November to 4 December 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Nuno Borges | 91 | 1 | ||
 Austria | Jurij Rodionov | 122 | 2 | |
 Sweden | Elias Ymer | 130 | 3 | |
| France | Geoffrey Blancaneaux | 135 | 4 | |
 Australia | Aleksandar Vukic | 140 | 5 | |
 Kazakhstan | Timofey Skatov | 146 | 6 | |
 Italy | Luciano Darderi | 178 | 7 | |
| Italy | Riccardo Bonadio | 191 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Raphaël Collignon
Denis Istomin Maximilian Neuchrist Gauthier OnclinSee main article: 2022 Maia Challenger – Singles.
Luca Van Assche def. Maximilian Neuchrist 3–6, 6–4, 6–0.See main article: 2022 Maia Challenger – Doubles.
Julian Cash / Henry Patten def. Nuno Borges / Francisco Cabral 6–3, 3–6, [10–8].