| Year: | 2022 |
| Team: | Louisville Cardinals |
| Sport: | Football |
| Conference: | Atlantic Coast Conference |
| Division: | Atlantic Division |
| Short Conf: | ACC |
| Record: | 8–5 |
| Conf Record: | 4–4 |
| Head Coach: | Scott Satterfield |
| Hc Year: | 4th |
| Hc Games: | regular season |
| Head Coach2: | Deion Branch |
| Hc Games2: | interim; bowl game |
| Off Coach: | Lance Taylor |
| Oc Year: | 1st |
| Off Scheme: | Spread option |
| Def Coach: | Bryan Brown |
| Dc Year: | 4th |
| Codef Coach1: | Wesley McGriff |
| Codc1 Year: | 1st |
| Def Scheme: | 4–2–5 |
| Stadium: | Cardinal Stadium |
| Champion: | Fenway Bowl champion |
| Bowl: | Fenway Bowl |
| Bowl Result: | W 24–7 vs. Cincinnati |
The 2022 Louisville Cardinals football team represented the University of Louisville during the 2022 NCAA Division I FBS football season. This was the team's fourth season under head coach Scott Satterfield. The Cardinals played their home games at Cardinal Stadium in Louisville, Kentucky, and competed as a member of the Atlantic Coast Conference (ACC).
On December 5, Satterfield announced he would be leaving Louisville to become the head coach at Cincinnati.[1] Director of player personal, Deion Branch, who played wide receiver for Louisville in 2000 and 2001, was named interim head coach for the Cardinals' bowl game.[2]
See also: 2022 Syracuse Orange football team.
See also: 2022 UCF Knights football team.
See also: 2022 Florida State Seminoles football team.
See also: 2022 South Florida Bulls football team.
See also: 2022 Boston College Eagles football team.
See also: 2022 Virginia Cavaliers football team.
See also: 2022 Pittsburgh Panthers football team.
See also: 2022 Wake Forest Demon Deacons football team.
See also: 2022 James Madison Dukes football team.
See also: 2022 Clemson Tigers football team.
See also: 2022 NC State Wolfpack football team.
See also: 2022 Kentucky Wildcats football team.
See also: 2022 Cincinnati Bearcats football team and 2022 Fenway Bowl.