| Date: | 25 April–1 May 2022 |
| Edition: | 13th |
| Surface: | Clay / Outdoor |
| Location: | Charleston, South Carolina, United States |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $100,000 |
| Champs: |  Taylor Townsend |
| Champd: |  Katarzyna Kawa / Aldila Sutjiadi |
The 2022 LTP Charleston Pro Tennis was a professional tennis tournament played on outdoor clay courts. It was the thirteenth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Charleston, South Carolina, United States between 25 April and 1 May 2022.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Romania | Irina Bara | 104 | 1 | |
| Tatjana Maria | 113 | 2 | ||
| United States | Katie Volynets | 119 | 3 | |
| United States | Hailey Baptiste | 125 | 4 | |
 China | Wang Xiyu | 127 | 5 | |
| United States | CoCo Vandeweghe | 130 | 6 | |
 Italy | Lucrezia Stefanini | 153 | 7 | |
| Poland | Katarzyna Kawa | 154 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry as a special exempt:
The following players received entry from the qualifying draw:
Françoise Abanda
Gabriela Cé Alexa Graham Elizabeth Halbauer Catherine Harrison Whitney Osuigwe
Akvilė Paražinskaitė Chanelle Van NguyenSee main article: 2022 LTP Charleston Pro Tennis – Singles.
Taylor Townsend def. Wang Xiyu, 6–3, 6–2See main article: 2022 LTP Charleston Pro Tennis – Doubles.
Katarzyna Kawa / Aldila Sutjiadi def. Sophie Chang / Angela Kulikov, 6–1, 6–4