| Date: | 28 August–4 September 2022 |
| Edition: | 9th |
| Surface: | Clay / Outdoor |
| Location: | Prague, Czech Republic |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Réka Luca Jani |
| Champd: |  Elixane Lechemia / Julia Lohoff |
The 2022 Kuchyně Gorenje Prague Open was a professional tennis tournament played on outdoor clay courts. It was the ninth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Prague, Czech Republic between 28 August and 4 September 2022.[1]
See main article: 2022 Kuchyně Gorenje Prague Open – Singles.
Réka Luca Jani def. Noma Noha Akugue, 6–3, 7–6(7–4)See main article: 2022 Kuchyně Gorenje Prague Open – Doubles.
Elixane Lechemia / Julia Lohoff def. 
Linda Klimovičová / Dominika Šalková, 7–5, 7–5| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Austria | Julia Grabher | 122 | 1 | |
| Hungary | Réka Luca Jani | 134 | 2 | |
 Argentina | María Lourdes Carlé | 175 | 3 | |
| Despina Papamichail | 187 | 4 | ||
| Czech Republic | Jesika Malečková | 210 | 5 | |
 Macedonia, the former Yugoslav Republic of | Lina Gjorcheska | 237 | 6 | |
 Bosnia and Herzegovina | Dea Herdželaš | 251 | 7 | |
 Turkey | Çağla Büyükakçay | 264 | 8 | |
| France | Carole Monnet | 269 | 9 | |
 Spain | Ángela Fita Boluda | 274 | 10 | |
| Lea Bošković | 276 | 11 | ||
 Brazil | Gabriela Cé | 289 | 12 | |
| Eva Vedder | 290 | 13 | ||
| Spain | Irene Burillo Escorihuela | 291 | 14 | |
| Daniela Seguel | 293 | 15 | ||
| Vera Lapko | 299 | 16 |
The following players received wildcards into the singles main draw:
Linda Klimovičová Aneta Laboutková Julie Štruplová Tereza Valentová Karolína VlčkováThe following players received entry from the qualifying draw:
Funa Kozaki Misaki Matsuda Barbora Michálková
Chiara Scholl Ivana Šebestová
Aurora ZantedeschiThe following player received entry as a lucky loser:
