| Date: | 11–17 July (men) 1–7 August (women) |
| Edition: | 3rd (men) 1st (women) |
| Category: | ATP Challenger 100 (men) WTA 125 (women) |
| Draw: | 32S/24Q/16D (men) 32S/15Q/16D (women) |
| Prize Money: | €90,280 (men) $115,000 (women) |
| Surface: | Clay |
| Location: | Iași, Romania |
| Venue: | Baza sportiva Ciric |
| Champms: |  Felipe Meligeni Alves |
| Champws: |  Ana Bogdan |
| Champmd: |  Geoffrey Blancaneaux /  Renzo Olivo |
| Champwd: | Darya Astakhova / Andreea Roșca |
The 2022 Iași Open was a professional tennis tournament played on clay courts. It was the third edition of the men's tournament which was part of the 2022 ATP Challenger Tour[1] and first edition of the women's tournament which was part of 2022 WTA 125 tournaments.[2] It took place in Iași, Romania between 11 and 17 July 2022 for the men and between 1 and 7 August for the women.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Czech Republic | Jiří Lehečka | 72 | 1 | |
 Spain | Pablo Andújar | 100 | 2 | |
| Czech Republic | Zdeněk Kolář | 119 | 3 | |
| Alexander Shevchenko | 158 | 4 | ||
| France | Geoffrey Blancaneaux | 165 | 5 | |
| Czech Republic | Dalibor Svrčina | 178 | 6 | |
| Argentina | Renzo Olivo | 186 | 7 | |
| Brazil | Felipe Meligeni Alves | 197 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Joris De Loore Nicolae Frunză Ștefan Paloși José Pereira Matheus Pucinelli de Almeida
Ilya SnițariThe following player received entry as lucky losers:
Oleg Prihodko| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Viktorija Golubic | 103 | 1 | ||
 Hungary | Panna Udvardy | 106 | 2 | |
| Romania | Ana Bogdan | 108 | 3 | |
 Serbia | Olga Danilović | 111 | 4 | |
| Brazil | Laura Pigossi | 113 | 5 | |
| France | Kristina Mladenovic | 116 | 6 | |
| Romania | Irina Bara | 125 | 7 | |
 Georgia | Ekaterine Gorgodze | 126 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Lavinia Tănăsie
Olivia Tjandramulia
Julia Grabher → replaced by Nadia Podoroska Alexandra Cadanțu-Ignatik
Dea Herdželaš Gabriela Lee → replaced by Lavinia Tănăsie Laura Pigossi → replaced by Olivia Tjandramulia
Anna Karolína Schmiedlová → replaced by Despina Papamichail| Country | Player | Country | Player | Rank† | Seed | |
|---|---|---|---|---|---|---|
| Czech Republic | Anastasia Dețiuc | France | Elixane Lechemia | 242 | 1 | |
| Angelina Gabueva | Anastasia Zakharova | 275 | 2 | |||
| Beatrice Gumulya | Australia | Olivia Tjandramulia | 347 | 3 | ||
| Hungary | Réka Luca Jani | Hungary | Panna Udvardy | 348 | 4 |
The following pair received a wildcard entry into main draw:
Daria Munteanu / Catrinel OnciulescuThe following pair received entry using a protected ranking:
Maja Chwalińska / Jesika Malečková → replaced by Andreea Prisăcariu / Anita Wagner Anastasia Dețiuc / Miriam Kolodziejová → replaced by Anastasia Dețiuc / Elixane Lechemia Elixane Lechemia / Laura Ioana Paar → replaced by Paula Ormaechea / 
Prarthana ThombareSee main article: 2022 Iași Open – Men's singles.
Felipe Meligeni Alves def. Pablo Andújar 6–3, 4–6, 6–2.See main article: 2022 Iași Open – Women's singles.
Ana Bogdan def. Panna Udvardy 6–2, 3–6, 6–1See main article: 2022 Iași Open – Men's doubles.
Geoffrey Blancaneaux / Renzo Olivo def. 
Diego Hidalgo / 
Cristian Rodríguez 6–4, 2–6, [10–6].See main article: 2022 Iași Open – Women's doubles.
Andreea Roșca def. Réka Luca Jani / Panna Udvardy 7–5, 5–7, [10–7]
