See main article: 2022 Heilbronner Neckarcup.
Nathaniel Lammons and Jackson Withrow were the defending champions[1] but only Withrow chose to defend his title, partnering Denys Molchanov. Withrow lost in the quarterfinals to Andrej Martin and Tristan-Samuel Weissborn.
Nicolás Barrientos and Miguel Ángel Reyes-Varela won the title after defeating Jelle Sels and Bart Stevens 7–5, 6–3 in the final.