| Date: | 17–23 October |
| Edition: | 7th |
| Category: | ATP Tour 250 Series |
| Prize Money: | €648,130 |
| Draw: | 28S / 16D |
| Surface: | Hard (indoor) |
| Location: | Antwerp, Belgium |
| Venue: | Lotto Arena |
| Champs: |  Félix Auger-Aliassime |
| Champd: | Tallon Griekspoor / Botic van de Zandschulp |
| Main Name: | European Open (tennis) European Open |
The 2022 European Open was a men's tennis tournament played on indoor hard courts. It was the seventh edition of the European Open and part of the ATP Tour 250 series of the 2022 ATP Tour. It took place at the Lotto Arena in Antwerp, Belgium, from 17 October until 23 October 2022.[1]
See main article: 2022 European Open – Singles.
Félix Auger-Aliassime def. 
Sebastian Korda, 6–3, 6–4See main article: 2022 European Open – Doubles.
Rohan Bopanna / Matwé Middelkoop, 3–6, 6–3, [10–5]| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Poland | Hubert Hurkacz | 11 | 1 | |
| Canada | Félix Auger-Aliassime | 13 | 2 | |
 Argentina | Diego Schwartzman | 18 | 3 | |
| Karen Khachanov | 19 | 4 | ||
 United Kingdom | Dan Evans | 25 | 5 | |
| Argentina | Francisco Cerúndolo | 29 | 6 | |
| Botic van de Zandschulp | 34 | 7 | ||
 Japan | Yoshihito Nishioka | 41 | 8 |
The following players received wildcards into the singles main draw:
The following player was accepted directly into the main draw using a protected ranking:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Alexander Bublik → replaced by Marc-Andrea Hüsler
David Goffin Andy Murray → replaced by 
Manuel Guinard Arthur Rinderknech → replaced by Geoffrey Blancaneaux| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Colombia | Juan Sebastián Cabal | Colombia | Robert Farah | 30 | 1 | |
| India | Rohan Bopanna | Matwé Middelkoop | 45 | 2 | ||
| Kevin Krawietz | Andreas Mies | 56 | 3 | |||
| France | Nicolas Mahut | France | Édouard Roger-Vasselin | 67 | 4 |
The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
Marcos Giron / Sebastian Korda → replaced by 
Ivan Sabanov / Matej Sabanov
Marcel Granollers / Horacio Zeballos → replaced by Sander Arends / David Pel